Title : Sensitive UHPLC-MS/MS quantification method for 4β- and 4α-hydroxycholesterol in plasma for accurate CYP3A phenotyping.

Pub. Date : 2022 Mar

PMID : 35181316






1 Functional Relationships(s)
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1 4beta-Hydroxycholesterol (4beta-OHC) is formed by CYP3A4 and CYP3A5 and has drawn attention as an endogenous phenotyping probe for CYP3A activity. cholest-5-ene-3,4-diol cytochrome P450 family 3 subfamily A member 5 Homo sapiens