Title : Fangchinoline inhibited proliferation of neoplastic B-lymphoid cells and alleviated Sjögren's syndrome-like responses in NOD/Ltj mice via the Akt/mTOR pathway.

Pub. Date : 2022 Feb 17

PMID : 35176991






2 Functional Relationships(s)
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1 OBJECTIVE: This study aimed to identify the potential role of Fangchinoline in the treatment of SS via altering Akt/mTOR signaling. fangchinoline mechanistic target of rapamycin kinase Homo sapiens
2 In vitro, Fangchinoline and LY294002 inhibited proliferation, induced cell cycle arrest, and promoted apoptosis in Raji and Daudi cells by altering Akt/mTOR signaling. fangchinoline mechanistic target of rapamycin kinase Homo sapiens