Title : Design and Activity of Novel Oxadiazole Based Compounds That Target Poly(ADP-ribose) Polymerase.

Pub. Date : 2022 Jan 21

PMID : 35163965






1 Functional Relationships(s)
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1 Treatment of MCF-7 cells with compounds 5u and 5s produced PARP cleavage, H2AX phosphorylation and CASPASE-3 activation comparable to that observed with Olaparib. olaparib caspase 3 Homo sapiens