Title : miR-132-3p Modulates DUSP9-Dependent p38/JNK Signaling Pathways to Enhance Inflammation in the Amnion Leading to Labor.

Pub. Date : 2022 Feb 7

PMID : 35163786






2 Functional Relationships(s)
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1 Silencing DUSP9 was found to facilitate the expression of proinflammatory cytokines and COX2 as well as PGE2 secretion in WISH cells, which could be attenuated by p38 inhibitor SB203580 or JNK inhibitor SP600125. Dinoprostone mitogen-activated protein kinase 8 Mus musculus
2 Collectively, miR-132-3p might participate in inflammation and PGE2 release via targeting DUSP9-dependent p38 and JNK signaling pathways to cause preterm birth. Dinoprostone mitogen-activated protein kinase 8 Mus musculus