Title : RNA-Cholesterol Nanoparticles Function as Potent Immune Activators via TLR7 and TLR8.

Pub. Date : 2021

PMID : 35126343






1 Functional Relationships(s)
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1 Cholesterol-conjugated RNA (RNA-chol) formed nanoparticles that were superior to RNA-liposomes complexes in regard to induction of type I interferon from human and murine plasmacytoid dendritic cells as well as proinflammatory cytokine production (e.g. TNF-alpha, IL12p70 or IL-6) in human monocytes. Cholesterol interleukin 6 Homo sapiens