Title : Nicorandil alleviates cardiac remodeling and dysfunction post -infarction by up-regulating the nucleolin/autophagy axis.

Pub. Date : 2022 Apr

PMID : 35122988






1 Functional Relationships(s)
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1 Nicorandil up-regulated the expression of nucleolin, promoted autophagic flux, and decreased the expressions of TGF-beta1 and phosphorylated Smad2/3, while enhanced the expression of BMP-7 and phosphorylated Smad1 in myocardium. Nicorandil transforming growth factor, beta 1 Rattus norvegicus