Pub. Date : 2021
PMID : 35115924
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In this study, pharmacological activation of TRPV1 with the TRPV1 agonist capsaicin induced autophagy in a TRPV1-dependent manner in both primary microglia and BV2 cells. | Capsaicin | transient receptor potential cation channel, subfamily V, member 1 | Mus musculus |
2 | In this study, pharmacological activation of TRPV1 with the TRPV1 agonist capsaicin induced autophagy in a TRPV1-dependent manner in both primary microglia and BV2 cells. | Capsaicin | transient receptor potential cation channel, subfamily V, member 1 | Mus musculus |
3 | In this study, pharmacological activation of TRPV1 with the TRPV1 agonist capsaicin induced autophagy in a TRPV1-dependent manner in both primary microglia and BV2 cells. | Capsaicin | transient receptor potential cation channel, subfamily V, member 1 | Mus musculus |
4 | TRPV1 agonist capsaicin decreased amyloid and phosphorylated tau pathology and reversed memory deficits by promoting microglia activation, metabolism, and autophagy in 3xTg mice. | Capsaicin | transient receptor potential cation channel, subfamily V, member 1 | Mus musculus |
5 | These results indicate that TRPV1 was a potential therapeutic target for AD, which suggests that capsaicin should be further assessed as a possible treatment for AD. | Capsaicin | transient receptor potential cation channel, subfamily V, member 1 | Mus musculus |