Title : Attenuation of SARS-CoV-2 infection by losartan in human kidney organoids.

Pub. Date : 2022 Feb 18

PMID : 35106453






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Losartan, an angiotensin II receptor blocker being tested in COVID-19 patients, inhibited angiotensin II mediated internalization of ACE2, upregulated interferon stimulated genes (IFITM1 and BST2) known to restrict viral entry, and attenuated the infection of proximal tubule cells by SARS-CoV-2. Losartan angiotensin converting enzyme 2 Homo sapiens