Title : Alzheimer's disease therapy based on acetylcholinesterase inhibitor/blocker effects on voltage-gated potassium channels.

Pub. Date : 2022 Mar

PMID : 35098414






4 Functional Relationships(s)
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1 To enhance the declined level of acetylcholine (ACh) resulting from loss of cholinergic neurons, acetylcholinesterase (AChE) inhibitors are developed and successfully approved for AD treatment in the clinic, with a limited therapeutic effectiveness. Acetylcholine acetylcholinesterase (Cartwright blood group) Homo sapiens
2 To enhance the declined level of acetylcholine (ACh) resulting from loss of cholinergic neurons, acetylcholinesterase (AChE) inhibitors are developed and successfully approved for AD treatment in the clinic, with a limited therapeutic effectiveness. Acetylcholine acetylcholinesterase (Cartwright blood group) Homo sapiens
3 To enhance the declined level of acetylcholine (ACh) resulting from loss of cholinergic neurons, acetylcholinesterase (AChE) inhibitors are developed and successfully approved for AD treatment in the clinic, with a limited therapeutic effectiveness. Acetylcholine acetylcholinesterase (Cartwright blood group) Homo sapiens
4 To enhance the declined level of acetylcholine (ACh) resulting from loss of cholinergic neurons, acetylcholinesterase (AChE) inhibitors are developed and successfully approved for AD treatment in the clinic, with a limited therapeutic effectiveness. Acetylcholine acetylcholinesterase (Cartwright blood group) Homo sapiens