Title : Unique Oxidative Metabolism of Bufalin Generates Two Reactive Metabolites That Strongly Inactivate Human Cytochrome P450 3A.

Pub. Date : 2022 Mar 10

PMID : 35094507






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 These findings expand the current knowledge of CYP inactivators and suggest that some steroids bearing the 3-keto group may trigger time-dependent CYP3A inactivation. Steroids cytochrome P450 family 3 subfamily A member 4 Homo sapiens