Title : Epigenetic landscape of drug responses revealed through large-scale ChIP-seq data analyses.

Pub. Date : 2022 Jan 24

PMID : 35073843






1 Functional Relationships(s)
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1 Using this approach, we predicted that: (1) cisplatin promotes the anti-tumor activity of TP53 family members but suppresses the cancer-inducing function of MYCs; (2) inhibition of RELA and E2F1 is pivotal for leflunomide to exhibit antiproliferative activity; and (3) CHD8 mediates valproic acid-induced autism. Cisplatin tumor protein p53 Homo sapiens