Title : Single-cell DNA-seq depicts clonal evolution of multiple driver alterations in osimertinib-resistant patients.

Pub. Date : 2022 Apr

PMID : 35066105






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 RESULTS: Among the 45 patients included in MATCH-R who progressed on osimertinib, nine developed a second targetable alteration (n = 2 FGFR3-TACC3, n = 1 KIF5B-RET, n = 1 STRN-ALK fusions; n = 2 BRAFV600E, n = 1 KRASG12V, n = 1 KRASG12R, n = 1 KRASG12D mutations). osimertinib ret proto-oncogene Homo sapiens