Title : MDH2 produced OAA is a metabolic switch rewiring the fuelling of respiratory chain and TCA cycle.

Pub. Date : 2022 Mar 1

PMID : 35063410






2 Functional Relationships(s)
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1 This new regulatory mechanism synergistically increases RC"s NADH oxidative capacity and rewires MDH2 driven anaplerosis of the TCA, preventing malate production from succinate to favour oxidation of cytosolic malate. malic acid malate dehydrogenase 2 Homo sapiens
2 This new regulatory mechanism synergistically increases RC"s NADH oxidative capacity and rewires MDH2 driven anaplerosis of the TCA, preventing malate production from succinate to favour oxidation of cytosolic malate. malic acid malate dehydrogenase 2 Homo sapiens