Title : Phosphorylation-Induced Ubiquitination and Degradation of PXR through CDK2-TRIM21 Axis.

Pub. Date : 2022 Jan 13

PMID : 35053380






2 Functional Relationships(s)
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1 As well-known CDK inhibitors, dinaciclib and kenpaullone stabilize PXR and result in elevated expression and activity of PXR-targeted DMETs, including carboxylesterases, CYP3A4 and P-gp. kenpaullone nuclear receptor subfamily 1 group I member 2 Homo sapiens
2 As well-known CDK inhibitors, dinaciclib and kenpaullone stabilize PXR and result in elevated expression and activity of PXR-targeted DMETs, including carboxylesterases, CYP3A4 and P-gp. kenpaullone nuclear receptor subfamily 1 group I member 2 Homo sapiens