Title : Phenols and terpenoids: natural products as inhibitors of NLRP3 inflammasome in cardiovascular diseases.

Pub. Date : 2022 Feb

PMID : 35039992






2 Functional Relationships(s)
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1 Docking results showed salvianolic acid B and ellagic acid in phenols, and oridonin and triptolide in terpenoids had a better binding activity with NLRP3, which can provide theoretical support for finding novel NLRP3 inflammasome inhibitors or lead compounds in the future. Ellagic Acid NLR family pyrin domain containing 3 Homo sapiens
2 Docking results showed salvianolic acid B and ellagic acid in phenols, and oridonin and triptolide in terpenoids had a better binding activity with NLRP3, which can provide theoretical support for finding novel NLRP3 inflammasome inhibitors or lead compounds in the future. Ellagic Acid NLR family pyrin domain containing 3 Homo sapiens