Title : 2-Hydroxyglutarate destabilizes chromatin regulatory landscape and lineage fidelity to promote cellular heterogeneity.

Pub. Date : 2022 Jan 11

PMID : 35021081






1 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 2HG induces loss of motif accessibility to the luminal-defining transcriptional factors FOXA1, FOXP1, and GATA3 and a shift from luminal to basal-like gene expression. Phenobarbital GATA binding protein 3 Homo sapiens