Title : Functional impact and targetability of PI3KCA, GNAS, and PTEN mutations in a spindle cell rhabdomyosarcoma with MYOD1 L122R mutation.

Pub. Date : 2022 Jan

PMID : 35012940






1 Functional Relationships(s)
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1 Dual PI3K/mTOR (LY3023414, bimiralisib) and AKT inhibitors (ipatasertib, afuresertib) induced dose-dependent reductions in cell growth. LY3023414 mechanistic target of rapamycin kinase Homo sapiens