Title : Niclosamide Suppresses Migration and Invasion of Human Osteosarcoma Cells by Repressing TGFBI Expression via the ERK Signaling Pathway.

Pub. Date : 2022 Jan 1

PMID : 35008910






1 Functional Relationships(s)
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1 Moreover, niclosamide significantly decreased the phosphorylation of ERK1/2 in U2OS cells and the combination treatment of the MEK inhibitor (U0126) and niclosamide resulted in the intensive inhibition of the TGFBI expression and the migratory ability in U2OS cells. U 0126 mitogen-activated protein kinase kinase 7 Homo sapiens