Title : Unraveling the differential impact of PAHs and dioxin-like compounds on AKR1C3 reveals the EGFR extracellular domain as a critical determinant of the AHR response.

Pub. Date : 2022 Jan

PMID : 34991250






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Exposure to benzo(a)pyrene (B(a)P) and dioxin-like polychlorinated biphenyl (PCB) 126 resulted in a rapid c-Src-mediated phosphorylation of EGFR. Benzo(a)pyrene epidermal growth factor receptor Homo sapiens
2 Exposure to benzo(a)pyrene (B(a)P) and dioxin-like polychlorinated biphenyl (PCB) 126 resulted in a rapid c-Src-mediated phosphorylation of EGFR. Benzo(a)pyrene epidermal growth factor receptor Homo sapiens