Title : Sildenafil (Viagra) Aggravates the Development of Experimental Abdominal Aortic Aneurysm.

Pub. Date : 2022 Jan 18

PMID : 34984916






2 Functional Relationships(s)
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1 PDE5 inhibitors have been used for treating erectile dysfunction, such as drug Viagra (sildenafil). Sildenafil Citrate phosphodiesterase 5A Homo sapiens
2 However, a few clinical cases have reported the association of Viagra usage with aortic dissection, and reduced PDE5A expression was found in human aortic aneurysm tissues. Sildenafil Citrate phosphodiesterase 5A Homo sapiens