Title : Interleukin 1 induces interleukin 1. II. Recombinant human interleukin 1 induces interleukin 1 production by adult human vascular endothelial cells.

Pub. Date : 1987 Sep 15

PMID : 3497983






3 Functional Relationships(s)
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1 EC stimulated with rIL-1 produced prostaglandin E2, which inhibits IL-1 production by other cell types and also decreases the responsiveness of thymocytes to IL-1. Dinoprostone interleukin 1 beta Homo sapiens
2 EC stimulated with rIL-1 produced prostaglandin E2, which inhibits IL-1 production by other cell types and also decreases the responsiveness of thymocytes to IL-1. Dinoprostone interleukin 1 beta Homo sapiens
3 When EC were exposed to rIL-1 in the presence of indomethacin (1 microgram/ml), which blocked prostaglandin E2 production, greater amounts of rIL-1-induced IL-1 release were detected, although the inhibitor did not affect IL-1-beta mRNA levels. Dinoprostone interleukin 1 beta Homo sapiens