Title : The Tongue Squamous Carcinoma Cell Line Cal27 Primarily Employs Integrin α6β4-Containing Type II Hemidesmosomes for Adhesion Which Contribute to Anticancer Drug Sensitivity.

Pub. Date : 2021

PMID : 34977030






1 Functional Relationships(s)
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1 Using a Cal27 tongue squamous cell carcinoma model, we have previously demonstrated that de novo expression of integrin alphaVbeta3 confers resistance to several anticancer drugs (cisplatin, mitomycin C and doxorubicin) through a mechanism involving downregulation of active Src, increased cell migration and invasion. Doxorubicin integrin subunit alpha V Homo sapiens