Title : GPR43 activation-mediated lipotoxicity contributes to podocyte injury in diabetic nephropathy by modulating the ERK/EGR1 pathway.

Pub. Date : 2022

PMID : 34975320






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Furthermore, GPR43 activation increased extracellular regulated protein kinases 1/2 (ERK1/2) activity and EGR1 expression in podocytes, which resulted in an increase in cholesterol influx and autophagy inhibition. Cholesterol mitogen-activated protein kinase 3 Mus musculus