Title : Crosstalk relationship between adiponectin receptors, PPAR-γ and α-adrenoceptors in renal vasculature of diabetic WKYs.

Pub. Date : 2022 Feb 15

PMID : 34973951






2 Functional Relationships(s)
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1 Diabetic WKYs had lower plasma adiponectin, higher creatinine clearance, urinary and fractional sodium excretion but were normalized to a greater extent in pioglitazone and adiponectin combined treatment. Pioglitazone adiponectin, C1Q and collagen domain containing Rattus norvegicus
2 Additionally, a degree of synergism exists between adiponectin and pioglitazone to a large extent compared to combination therapy with irbesartan (partial PPAR-gamma agonist) in attenuating the renal vascular receptiveness to adrenergic agonists. Pioglitazone adiponectin, C1Q and collagen domain containing Rattus norvegicus