Title : Upregulated hexokinase 2 expression induces the apoptosis of dopaminergic neurons by promoting lactate production in Parkinson's disease.

Pub. Date : 2022 Feb

PMID : 34973450






2 Functional Relationships(s)
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1 Mechanistically, lactate increases the activity of adenosine monophosphate-activated protein kinase (AMPK) and suppresses the phosphorylation of serine/threonine kinase 1 (Akt) and mammalian target of rapamycin (mTOR). Lactic Acid mechanistic target of rapamycin kinase Homo sapiens
2 Mechanistically, lactate increases the activity of adenosine monophosphate-activated protein kinase (AMPK) and suppresses the phosphorylation of serine/threonine kinase 1 (Akt) and mammalian target of rapamycin (mTOR). Lactic Acid mechanistic target of rapamycin kinase Homo sapiens