Pub. Date : 2021
PMID : 34966788
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Unraveling the Influence of K280 Acetylation on the Conformational Features of Tau Core Fragment: A Molecular Dynamics Simulation Study. | argatroban | microtubule associated protein tau | Homo sapiens |
| 2 | Mounting experiment evidence demonstrated the acetylation of a single-lysine residue K280 in the PHF6* was a critical event for the formation of pathological Tau amyloid deposits. | argatroban | microtubule associated protein tau | Homo sapiens |
| 3 | However, the underlying mechanisms by which K280 acetylation affects Tau aggregation at the atomic level remain elusive. | argatroban | microtubule associated protein tau | Homo sapiens |