Title : Effects of Polyphenols on P-Glycoprotein (ABCB1) Activity.

Pub. Date : 2021 Dec 2

PMID : 34959345






2 Functional Relationships(s)
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1 We tested the effect of 15 polyphenols of sour cherry origin on the basal and verapamil-stimulated ATPase activity of Pgp, calcein-AM and daunorubicin transport as well as on the conformation of Pgp using the conformation sensitive UIC2 mAb. Verapamil ATP binding cassette subfamily B member 1 Homo sapiens
2 We also investigated the effect of quercetin, naringenin and ellagic acid added in combination with verapamil on the transport activity of Pgp. Verapamil ATP binding cassette subfamily B member 1 Homo sapiens