Pub. Date : 2022 Feb
PMID : 34958913
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Emodin alleviates aortic valvular calcification by inhibiting the AKT/FOXO1 pathway. | Emodin | thymoma viral proto-oncogene 1 | Mus musculus |
| 2 | The elevations of calcium content in serum and valve, and calcium accumulation in valve and artery were suppressed by emodin in mice with valvular calcification after joint treatment with adenine and Vit D. In addition, p-AKT and p-FOXO1 were upregulated in PAVICs under high-calcium conditions, and this effect was reversed by emodin treatment. | Emodin | thymoma viral proto-oncogene 1 | Mus musculus |
| 3 | The elevations of calcium content in serum and valve, and calcium accumulation in valve and artery were suppressed by emodin in mice with valvular calcification after joint treatment with adenine and Vit D. In addition, p-AKT and p-FOXO1 were upregulated in PAVICs under high-calcium conditions, and this effect was reversed by emodin treatment. | Emodin | thymoma viral proto-oncogene 1 | Mus musculus |