Title : Protein kinase C-dependent and -independent pathways of proto-oncogene induction in human astrocytoma cells.

Pub. Date : 1987 Jun 5

PMID : 3495533






1 Functional Relationships(s)
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1 PMA, carbachol, and EGF all stimulated rapid accumulation of mRNA for the proto-oncogenes c-fos and c-myc in the normal cells; in the protein kinase C-deficient cells, carbachol and EGF, but not PMA, retained this effect, which was not mimicked by the calcium ionophore A23187. Tetradecanoylphorbol Acetate epidermal growth factor Homo sapiens