Title : In Vitro Evaluation of P-gp-Mediated Drug-Drug Interactions Using the RPTEC/TERT1 Human Renal Cell Model.

Pub. Date : 2022 Mar

PMID : 34935100






1 Functional Relationships(s)
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1 RESULTS: The data showed that drugs which are known P-gp inhibitors, including cyclosporin A, ketoconazole, and verapamil, caused great increases in rhodamine 123 retention, whereas noninhibitors did not affect the intracellular accumulation of the P-gp substrate. Verapamil ATP binding cassette subfamily B member 1 Homo sapiens