Title : Reduction of oxidative stress blunts the NLRP3 inflammatory cascade in LPS stimulated human gingival fibroblasts and oral mucosal epithelial cells.

Pub. Date : 2022 Feb

PMID : 34906776






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Flavocoxid is a mixed extract containing baicalin and catechin showing antioxidant effects and anti-inflammatory activity mainly due to a dual inhibition of inducible cyclooxygenase (COX-2), 5-lipoxygenase (5-LOX) and NLRP3 pathway. flavocoxid NLR family pyrin domain containing 3 Homo sapiens
2 These results suggest a correlation between oxidative stress and NLRP3 activation and indicate that flavocoxid suppresses the inflammatory storm that accompanies oral mucositis. flavocoxid NLR family pyrin domain containing 3 Homo sapiens