Pub. Date : 2022 Feb
PMID : 34904522
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | One of the major in vivo metabolic pathways of vixotrigine in humans is the hydrolysis of the carboxamide to form the carboxylic acid metabolite M14.The in vitro formation of M14 in human hepatocytes was inhibited by the carboxylesterase (CES) inhibitor Bis(4-nitrophenyl) phosphate in a concentration-dependent manner. | bis(4-nitrophenyl)phosphate | carboxylesterase 1 | Homo sapiens |