Title : The mitochondrial antioxidant SS-31 attenuated lipopolysaccharide-induced apoptosis and pyroptosis of nucleus pulposus cells via scavenging mitochondrial ROS and maintaining the stability of mitochondrial dynamics.

Pub. Date : 2021 Dec

PMID : 34903138






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Damaged mitochondria release dangerous molecules such as reactive oxygen species (ROS), activating the NLRP3 inflammasome. Reactive Oxygen Species NLR family pyrin domain containing 3 Homo sapiens
2 Damaged mitochondria release dangerous molecules such as reactive oxygen species (ROS), activating the NLRP3 inflammasome. Reactive Oxygen Species NLR family pyrin domain containing 3 Homo sapiens
3 The results indicate that SS-31 could inhibit NLRP3 inflammasome activation by limiting the production of mitochondrial ROS. Reactive Oxygen Species NLR family pyrin domain containing 3 Homo sapiens