Title : Design and synthesis of epigallocatechin (EGC) analogs selective to inhibit α-amylase over α-glucosidases via the incorporation of caffeine acid and its derivatives.

Pub. Date : 2022 Feb

PMID : 34896919






1 Functional Relationships(s)
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1 In this study twenty-one EGC-based derivatives selective to inhibit human pancreatic alpha-amylase (HPA), the enzyme at the top of the starch digestion pyramid, have been designed and synthesized in terms of the lead myricetin-caffeic acid conjugate 1 reported ever. Starch amylase alpha 2A Homo sapiens