Title : Prednisone stimulates white adipocyte browning via β3-AR/p38 MAPK/ERK signaling pathway.

Pub. Date : 2022 Jan 1

PMID : 34864064






1 Functional Relationships(s)
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1 KEY FINDINGS: Exposure to prednisone stimulated browning in 3 T3-L1 white adipocytes by increasing the expressions of core fat browning marker proteins (UCP1, PGC-1alpha and PRDM16) as well as beige-specific genes (Cd137, Cidea, Cited1, and Tbx1) via ATF2 and CREB activation mediated by p38 MAPK and ERK signaling, respectively. Prednisone uncoupling protein 1 (mitochondrial, proton carrier) Mus musculus