Title : Docetaxel-triggered SIDT2/NOX4/JNK/HuR signaling axis is associated with TNF-α-mediated apoptosis of cancer cells.

Pub. Date : 2022 Jan

PMID : 34863979






1 Functional Relationships(s)
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Protein Name
Organism
1 NOX4-stimulated ROS generation led to JNK-mediated phosphorylation of cytosolic HuR at Ser221, thereby increasing TNF-alpha protein expression by stabilizing TNF-alpha mRNA. ros mitogen-activated protein kinase 8 Homo sapiens