Title : Evaluation of the systemic and spinal antinociceptive effect of a new hybrid NSAID tetrahydropyran derivative.

Pub. Date : 2022 Mar

PMID : 34862806






2 Functional Relationships(s)
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1 In the thermal stimulation in animals injected with capsaicin, the compound showed antinociceptive effect by oral and intraplantar routes, besides to reducing the levels of TNF-alpha, IL-1beta and PGE2 in the paws previously administered with capsaicin. Capsaicin tumor necrosis factor Mus musculus
2 In the thermal stimulation in animals injected with capsaicin, the compound showed antinociceptive effect by oral and intraplantar routes, besides to reducing the levels of TNF-alpha, IL-1beta and PGE2 in the paws previously administered with capsaicin. Capsaicin tumor necrosis factor Mus musculus