Pub. Date : 2022 Mar 1
PMID : 34862201
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In beta-cells mTORC1 is inhibited while fasting, and is rapidly stimulated during refeeding by a single amino acid, leucine, and glucose. | Leucine | CREB regulated transcription coactivator 1 | Mus musculus |
| 2 | Reciprocally, stimulation of mTORC1 by elevated leucine and glucose, which is common in obesity, may promote hyperinsulinemia by inhibiting autophagy. | Leucine | CREB regulated transcription coactivator 1 | Mus musculus |