Title : Membrane model as key tool in the study of glutathione-s-transferase mediated anticancer drug resistance.

Pub. Date : 2022 Jan

PMID : 34861633






3 Functional Relationships(s)
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1 We found that both DOX and CDDP expand and affect the elasticity of MIX monolayers, but these effects are hindered when glutathione-s-transferase (GST) and its cofactor glutathione (GSH) are incorporated. Glutathione Mix paired-like homeobox Homo sapiens
2 We found that both DOX and CDDP expand and affect the elasticity of MIX monolayers, but these effects are hindered when glutathione-s-transferase (GST) and its cofactor glutathione (GSH) are incorporated. Glutathione Mix paired-like homeobox Homo sapiens
3 Changes are induced by DOX or CDDP on the polarization-modulated infrared reflection absorption spectroscopy (PM-IRRAS) data for MIX/GST/GSH monolayers, thus denoting some degree of interaction that is not sufficient to alter the monolayer mechanical properties. Glutathione Mix paired-like homeobox Homo sapiens