Pub. Date : 2021 Dec
PMID : 34855076
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Incubation of primary culture of pulmonary fibroblasts with non-opiate analogue of leuenkephalin (NALE; Phe-D-Ala-Gly-Phe-Leu-Arg, 0.1 muM) reduced generation of superoxide anion-radical (by 20.7%) and decreased the number of p53+ cells (by 40.2%) induced by exposure to H2O2 (60 muM). | Hydrogen Peroxide | tumor protein p53 | Homo sapiens |
2 | Incubation of pulmonary fibroblasts culture with peptide G (Phe-D-Ala-Gly-Phe-Leu-Gly, 0.1 muM) also significantly reduced the damaging effect of H2O2: the number of p53+ cells decreased by 73.5%, the area of cell nuclei returned to normal, and generation of superoxide anion-radical decreased by 18.4%. | Hydrogen Peroxide | tumor protein p53 | Homo sapiens |