Title : Assessing the Structural and Functional Similarity of Insulin Glargine Biosimilars.

Pub. Date : 2021 Dec 1

PMID : 34852652






5 Functional Relationships(s)
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1 Assessing the Structural and Functional Similarity of Insulin Glargine Biosimilars. Insulin Glargine insulin Homo sapiens
2 Only a few reports of thorough evaluation of the quality of insulin glargine biosimilars are available in literature. Insulin Glargine insulin Homo sapiens
3 Here, we examine the structural and functional similarity of biosimilars of insulin glargine, the first basal long-acting insulin analogue with respect to its innovator product (Lantus from Sanofi Aventis). Insulin Glargine insulin Homo sapiens
4 Here, we examine the structural and functional similarity of biosimilars of insulin glargine, the first basal long-acting insulin analogue with respect to its innovator product (Lantus from Sanofi Aventis). Insulin Glargine insulin Homo sapiens
5 CONCLUSIONS: While an overall structural and functional similarity was observed across insulin glargine biosimilars with respect to the innovator product, low amounts of product-related variants were seen in some biosimilars and these impact product stability. Insulin Glargine insulin Homo sapiens