Pub. Date : 2021 Dec 1
PMID : 34852652
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Assessing the Structural and Functional Similarity of Insulin Glargine Biosimilars. | Insulin Glargine | insulin | Homo sapiens |
2 | Only a few reports of thorough evaluation of the quality of insulin glargine biosimilars are available in literature. | Insulin Glargine | insulin | Homo sapiens |
3 | Here, we examine the structural and functional similarity of biosimilars of insulin glargine, the first basal long-acting insulin analogue with respect to its innovator product (Lantus from Sanofi Aventis). | Insulin Glargine | insulin | Homo sapiens |
4 | Here, we examine the structural and functional similarity of biosimilars of insulin glargine, the first basal long-acting insulin analogue with respect to its innovator product (Lantus from Sanofi Aventis). | Insulin Glargine | insulin | Homo sapiens |
5 | CONCLUSIONS: While an overall structural and functional similarity was observed across insulin glargine biosimilars with respect to the innovator product, low amounts of product-related variants were seen in some biosimilars and these impact product stability. | Insulin Glargine | insulin | Homo sapiens |