Title : Redox-sensitive cyclophilin A elicits chemoresistance through realigning cellular oxidative status in colorectal cancer.

Pub. Date : 2021 Nov 30

PMID : 34852234






1 Functional Relationships(s)
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1 Our results show that CypA forms an intramolecular disulfide bond between Cys115 and Cys161 upon oxidative stress and the oxidized cysteines in CypA are recycled to a reduced state by peroxiredoxin-2 (PRDX2). Disulfides peptidylprolyl isomerase A Homo sapiens