Title : RSPO2 and RANKL signal through LGR4 to regulate osteoclastic premetastatic niche formation and bone metastasis.

Pub. Date : 2022 Jan 18

PMID : 34847079






1 Functional Relationships(s)
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1 These findings provide unique insights into the functional role of OPs as key components of pre-metastatic niche for BCa bone metastasis, indicate RSPO2/RANKL-LGR4 signaling as a promising target for inhibiting BCa bone metastasis. OPS leucine-rich repeat-containing G protein-coupled receptor 4 Mus musculus