Title : Multi-Target Effects of Novel Synthetic Coumarin Derivatives Protecting Aβ-GFP SH-SY5Y Cells against Aβ Toxicity.

Pub. Date : 2021 Nov 9

PMID : 34831318






1 Functional Relationships(s)
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1 In SH-SY5Y cells expressing the GFP-tagged Abeta-folding reporter, both ZN compounds reduced Abeta aggregation, oxidative stress, activities of caspase-1 and AChE, as well as increased neurite outgrowth. Zinc amyloid beta precursor protein Homo sapiens