Title : Scleroderma-like Impairment in the Network of Telocytes/CD34+ Stromal Cells in the Experimental Mouse Model of Bleomycin-Induced Dermal Fibrosis.

Pub. Date : 2021 Nov 17

PMID : 34830288






2 Functional Relationships(s)
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1 The analyses of skin samples from mice treated with bleomycin for different times by either TEM or double immunostaining and immunoblotting for the CD34/alpha-SMA antigens collectively suggested that, although a few TCs may transition to alpha-SMA+ myofibroblasts in the early disease stage, most of these cells rather undergo degeneration, and then are lost. Bleomycin actin alpha 2, smooth muscle, aorta Mus musculus
2 The analyses of skin samples from mice treated with bleomycin for different times by either TEM or double immunostaining and immunoblotting for the CD34/alpha-SMA antigens collectively suggested that, although a few TCs may transition to alpha-SMA+ myofibroblasts in the early disease stage, most of these cells rather undergo degeneration, and then are lost. Bleomycin actin alpha 2, smooth muscle, aorta Mus musculus