Title : Emodin alleviates sepsis-mediated lung injury via inhibition and reduction of NF-kB and HMGB1 pathways mediated by SIRT1.

Pub. Date : 2022 Mar

PMID : 34806822






1 Functional Relationships(s)
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1 In lipopolysaccharide (LPS) treated cell model, emodin treatment markedly decreased LPS-induced release of IL-1, IL-6, and tumor necrosis factor (TNF)-alpha, inhibited LPS-induced cell apoptosis and suppressed protein levels of P-P65/P65 and HMGB1. Emodin tumor necrosis factor Mus musculus