Title : Novel Bile Acid-Dependent Mechanisms of Hepatotoxicity Associated with Tyrosine Kinase Inhibitors.

Pub. Date : 2022 Feb

PMID : 34794962






1 Functional Relationships(s)
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1 The increase in NTCP protein abundance correlated with increased function; dasatinib and pazopanib increased hepatocyte uptake clearance (CLuptake) of taurocholic acid, a probe bile acid substrate, up to 1.4 fold. Taurocholic Acid solute carrier family 10 member 1 Homo sapiens