Pub. Date : 2021 Dec
PMID : 34794890
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Isoliquiritigenin alleviates P. gingivalis-LPS/ATP-induced pyroptosis by inhibiting NF-kappaB/ NLRP3/GSDMD signals in human gingival fibroblasts. | isoliquiritigenin | NLR family pyrin domain containing 3 | Homo sapiens |
| 2 | OBJECTIVE: To investigate whether pyroptosis is induced by Porphyromonas gingivalis-lipopolysaccharide (P. gingivalis-LPS)/ adenosine triphosphate (ATP) through NF-kappaB/NLRP3/GSDMD signaling in human gingival fibroblasts (HGFs) and whether isoliquiritigenin (ISL) alleviates pyroptosis by inhibition of NF-kappaB/NLRP3/GSDMD signals. | isoliquiritigenin | NLR family pyrin domain containing 3 | Homo sapiens |