Title : Ghrelin enhances cisplatin sensitivity in HO-8910 PM human ovarian cancer cells.

Pub. Date : 2021 Nov 17

PMID : 34789301






2 Functional Relationships(s)
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1 However, under the treatment of ghrelin, cisplatin treatment exhibited a stronger effect on inhibiting P21 expression, upregulating p-CDK1 and cyclin B1 expression, and blocking cell cycle progression. Cisplatin cyclin dependent kinase 1 Homo sapiens
2 Mechanistically, ghrelin promoted S phase cell cycle arrest and upregulated p-CDK1 and cyclin B1 expression induced by cisplatin via inhibition of p38. Cisplatin cyclin dependent kinase 1 Homo sapiens