Title : Effect of Palrnatine on lipopolysaccharide-induced acute lung injury by inhibiting activation of the Akt/NF‍-κB pathway.

Pub. Date : 2021 Nov 15

PMID : 34783223






3 Functional Relationships(s)
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1 Through molecular dynamics simulation, we observed that Pa was bound to the catalytic pocket of Akt and effectively inhibited the biological activity of Akt. Protactinium thymoma viral proto-oncogene 1 Mus musculus
2 Through molecular dynamics simulation, we observed that Pa was bound to the catalytic pocket of Akt and effectively inhibited the biological activity of Akt. Protactinium thymoma viral proto-oncogene 1 Mus musculus
3 These results indicated that Pa significantly relieves LPS-induced ALI by activating the Akt/NF-kappaB signaling pathway. Protactinium thymoma viral proto-oncogene 1 Mus musculus